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Opioid Treatment Program

Opioid Treatment Program. An OTP is defined as “a program or practitioner engaged in treatment of individuals with an opioid agonist medication”


Opioids are powerful pain relievers. Some are made from the poppy plant. Others are produced in a laboratory. Those are called synthetic opioids.

You can take opioids to relieve acute pain, like after surgery. Or you can take them longer term to manage chronic pain.

These drugs come in immediate-release and extended-release formulas. Sometimes they’re combined with another pain reliever, like acetaminophen.

Treatment varies but may include discontinuing the drug. Medication such as methadone can help alleviate the symptoms of withdrawal and cravings. Pairing medication with inpatient or support programmed generally has the most success.

Methadone is a full mu-opioid receptor agonist, typically used as a replacement therapy for heroin or other opioid dependence. Methadone’s slow onset of action when taken orally and long elimination half-life (24–36 hours) allows it to be used as either a maintenance therapy or detoxification agent .

2.1.1. Maintenance

Methadone has been used as a substitution for heroin or other opiates and, through the mechanisms of tolerance and cross-tolerance, prevents opioid intoxication and withdrawal. Adequate dosing ranges from 80 – 150 mg, typically beginning with a daily dose of 20–30 mg with increases of 5 or 10 mg until the optimal dose is reached. Methadone maintenance treatment (MMT) is associated with retention in treatment, and reductions in IV drug use, criminal activity, and HIV risk behaviors and mortality . It is currently the most successful treatment for chronic opioid dependence, although not without fairly substantial financial and personal costs to individuals participating in this therapy .


opioid treatment

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opioid treatment



opioid treatment



opioid treatment


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